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Rheb activates AMPK and reduces p27Kip1 levels in Tsc2-null cells via mTORC1-independent mechanisms: implications for cell proliferation and tumorigenesis

Reduces P27kip1 LevelsSignal TransductionSignaling PathwayCell RegulationMedicineTsc2-null CellsMtorc1-independent MechanismsCell BiologyTumor SuppressorCancer BiologyRadiation OncologyCell SignalingTumor Biology