Publication | Open Access

Discovery and biological evaluation of potent, selective, orally bioavailable, pyrazine-based blockers of the Nav1.8 sodium channel with efficacy in a model of neuropathic pain

Nav1.8 Sodium ChannelPyrazine-based BlockersPain MedicinePharmacologyNeuropathic PainPharmacological AgentNeuropharmacologyExperimental PharmacologyPharmacotherapyPain MechanismMedicineAnalgesicsDrug DiscoveryPain Research