Isozyme selective inhibition of cGMP-stimulated cyclic nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl) adenine

Adenosine 3‘,5‘-Phosphate in Biological Materials

R.W. Butcher, Earl W. Sutherland · Journal of Biological Chemistry · 1962 · 2.1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

ADENOSINE-DEAMINASE DEFICIENCY IN TWO PATIENTS WITH SEVERELY IMPAIRED CELLULAR IMMUNITY

E.R. Giblett, JeanneE. Anderson, Flossie Cohen et al. · The Lancet · 1972 · 1.7K citations

Life Sciences, Immunology, Molecular Genetics +9

The identification of a new cyclic nucleotide phosphodiesterase activity in human and guinea-pig cardiac ventricle. Implications for the mechanism of action of selective phosphodiesterase inhibitors

M. L. REEVES, B. K. Leigh, P. England · Biochemical Journal · 1987 · 304 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Enzyme inhibitors. 26. Bridging hydrophobic and hydrophilic regions on adenosine deaminase with some 9-(2-hydroxy-3-alkyl)adenines

Howard J. Schaeffer, Charles F. Schwender · Journal of Medicinal Chemistry · 1974 · 295 citations

Life Sciences, Biochemistry, Molecular Biology +10

Adenosine Inhibition of Lymphocyte-Mediated Cytolysis: Possible Role of Cyclic Adenosine Monophosphate

Gerald Wolberg, Thomas P. Zimmerman, Kay Hiemstra et al. · Science · 1975 · 268 citations

Life Sciences, Biochemistry, Immunology +13