Synthesis and anticancer activity of some novel 5,6-fused hybrids of juglone based 1,4-naphthoquinones

A simple technique for quantifying apoptosis in 96-well plates

Deborah Ribble, Nathaniel B. Goldstein, David A. Norris et al. · BMC Biotechnology · 2005 · 850 citations · Full text

Life Sciences, Cell Biology, Apoptosis +10

Cytotoxic Action of Juglone and Plumbagin:  A Mechanistic Study Using HaCaT Keratinocytes

Johnson J. Inbaraj, Colin F. Chignell · Chemical Research in Toxicology · 2003 · 330 citations

Life Sciences, Biochemistry, Dermatology +17

2- and 3-Substituted 1,4-Naphthoquinone Derivatives as Subversive Substrates of Trypanothione Reductase and Lipoamide Dehydrogenase from <i>Trypanosoma</i> <i>c</i><i>ruzi</i>:  Synthesis and Correlation between Redox Cycling Activities and in Vitro Cytotoxicity

Laurence Salmon-Chemin, Eric Buisine, Vanessa Yardley et al. · Journal of Medicinal Chemistry · 2001 · 257 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

The chemical and biological activities of quinones: overview and implications in analytical detection

Nahed El‐Najjar, Hala Gali‐Muhtasib, Raimo A. Ketola et al. · Phytochemistry Reviews · 2011 · 257 citations

Natural Sciences, Biochemistry, Chemistry +11

Plumbagin (5-Hydroxy-2-methyl-1,4-naphthoquinone) Induces Apoptosis and Cell Cycle Arrest in A549 Cells through p53 Accumulation via c-Jun NH2-Terminal Kinase-Mediated Phosphorylation at Serine 15 in Vitro and in Vivo

Ya‐Ling Hsu, Chien-Yu Cho, Po‐Lin Kuo et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 208 citations

Medicine, Oncology, Pharmacology +17