Concepedia

The mAKAPβ scaffold regulates cardiac myocyte hypertrophy via recruitment of activated calcineurin

Jinliang Li, Alejandra Negro, Johanna Lopez, Andrea L. Bauman, Edward Henson, Kimberly L. Dodge‐Kafka, Michael S. Kapiloff

Journal of Molecular and Cellular Cardiology · 2009 · 72 citations · 28 references

Open access

Concepts

Cell PhysiologyCardiac MuscleCardiomyopathySignal TransductionMolecular PhysiologyMedicinePhysiologyMakapβ ScaffoldCell-matrix InteractionCardiac Myocyte HypertrophyCardiovascular PhysiologyMatrix BiologyCellular BiochemistryActivated CalcineurinCell BiologyCell SignalingCellular PhysiologyExtracellular Matrix

References

28

PKA Phosphorylation Dissociates FKBP12.6 from the Calcium Release Channel (Ryanodine Receptor)

Steven O. Marx, Steven Reiken, Yuji Hisamatsu et al. · Cell · 2000 · 2K citations · Full text

Molecular Pharmacology, Signal Transduction, Molecular Physiology +13

The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways

Kimberly L. Dodge‐Kafka, Joseph S. Soughayer, Geneviève C. Paré et al. · Nature · 2005 · 550 citations · Full text

Protein Function, Signal Transduction, Signaling Pathway +13

mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module

Kimberly L. Dodge · The EMBO Journal · 2001 · 500 citations · Full text

Protein Function, Molecular Physiology, Signal Transduction +10

AKAP79/150 Anchoring of Calcineurin Controls Neuronal L-Type Ca2+ Channel Activity and Nuclear Signaling

Seth F. Oliveria, Mark L. Dell’Acqua, William A. Sather · Neuron · 2007 · 337 citations · Full text

Nuclear Signaling, Signal Transduction, Molecular Physiology +11

Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling

Julian C. Braz, Orlando F. Bueno, Qiangrong Liang et al. · Journal of Clinical Investigation · 2003 · 306 citations · Full text