Radiopharmaceutical development of a freeze-dried kit formulation for the preparation of [99mTc-EDDA-HYNIC-D-Phe1, Tyr3]-octreotide, a somatostatin analog for tumor diagnosis

[111In-DTPA-D-Phe1]-octreotide, a potential radiopharmaceutical for imaging of somatostatin receptor-positive tumors: synthesis, radiolabeling and in vitro validation

Willem H. Bakker, Rainer Albert, Christian Bruns et al. · Life Sciences · 1991 · 327 citations

Medicine, Oncology, Radiology +16

99mTc-EDDA/HYNIC-TOC: a new 99mTc-labelled radiopharmaceutical for imaging somatostatin receptor-positive tumours: first clinical results and intra-patient comparison with 111In-labelled octreotide derivatives

Clemens Decristoforo, Stephen J. Mather, Witold Cholewiński et al. · European Journal of Nuclear Medicine and Molecular Imaging · 2000 · 176 citations

Medicine, Nuclear Medicine, Radiology +17

An intrapatient comparison of 99mTc-EDDA/HYNIC-TOC with 111In-DTPA-octreotide for diagnosis of somatostatin receptor-expressing tumors.

Michael Gabriel, Clemens Decristoforo, Eveline Donnemiller et al. · PubMed · 2003 · 169 citations

Medicine, Nuclear Medicine, Oncology +17

99mTc-HYNIC-[Tyr3]-octreotide for imaging somatostatin-receptor-positive tumors: preclinical evaluation and comparison with 111In-octreotide.

Clemens Decristoforo, Laura Meléndez‐Alafort, Jane Sosabowski et al. · PubMed · 2000 · 162 citations

Medicine, Nuclear Medicine, Pharmacology +17

Labeling a Hydrazino Nicotinamide-Modified Cyclic IIb/IIIa Receptor Antagonist with ^99mTc Using Aminocarboxylates as Coligands

Shuang Liu, David S. Edwards, Richard Looby et al. · Bioconjugate Chemistry · 1996 · 118 citations

Medicine, Medicinal Chemistry, Pharmacology +17