The EMBO Journal · 2003 · 300 citations · 69 references
Life SciencesMolecular BiologyNeuroscienceEpigeneticsMolecular NeuroscienceNeurodegenerationCaspase ActivationEpigenetic Regulation In NeurodegenerationHistone ProteinsMolecular Basis Of NeurodegenerationNeurodegenerative DiseasesNeurodegenerative DisordersCaspase SignalingCaspase-mediated ApoptosisHistone AcetyltransferasesHistone DeacetylasesNeurodegenerative Disease Epigenetics
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Phosphorylated CREB binds specifically to the nuclear protein CBP
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The CBP co-activator is a histone acetyltransferase
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Nuclear protein CBP is a coactivator for the transcription factor CREB
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Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
Joan S. Steffan, László Bodai, Judit Pallos et al. · Nature · 2001 · 1.2K citations · Full text
Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP
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