Neferine prevented hyperglycemia-induced endothelial cell apoptosis through suppressing ROS/Akt/NF-κB signal

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NF-κB Induces Expression of the Bcl-2 Homologue A1/Bfl-1 To Preferentially Suppress Chemotherapy-Induced Apoptosis

Cun-Yu Wang, Denis C. Guttridge, Marty W. Mayo et al. · Molecular and Cellular Biology · 1999 · 586 citations · Full text

Life Sciences, Cell Biology, Oncology +17

Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species

Tianzheng Yu, Shey‐Shing Sheu, James L. Robotham et al. · Cardiovascular Research · 2008 · 463 citations · Full text

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Effect of linagliptin monotherapy on glycaemic control and markers of <i>β</i> ‐cell function in patients with inadequately controlled type 2 diabetes: a randomized controlled trial

Stefano Del Prato, Anthony Barnett, Holger Huisman et al. · Diabetes Obesity and Metabolism · 2010 · 298 citations

Medicine, Pharmacology, Pharmacotherapy +17

Metformin Prevents High-Glucose–Induced Endothelial Cell Death Through a Mitochondrial Permeability Transition-Dependent Process

Dominique Détaille, Bruno Guigas, Christiane Chauvin et al. · Diabetes · 2005 · 258 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17