Polyelectrolyte Films Boost Progenitor Cell Differentiation into Endothelium‐like Monolayers

N. Berthélémy, Halima Kerdjoudj, Caroline Gaucher, Pierre Schaaf, Jean‐François Stoltz, Patrick Lacolley, Jean‐Claude Voegel, Patrick Menu

Advanced Materials · 2008 · 37 citations · 17 references

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Abstract

Rapid differentiation of endothelial progenitor cells (EPCs) into confluent mature endothelial cells is important in tissue engineering for the design of autologous, nonthrombotic, vascular grafts. A new method based on EPC culture on poly(sodium-4- styrene-sulfonate)/poly(allylamine hydrochloride), that is, polyelectrolyte-multilayer-coated substrates, reduces the time from two months to two weeks.

References

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