Synthesis of a variety of optically active hydroxylated heterocyclic compounds using epoxide hydrolase technology

Synthese von vier chiralen, elektrophilen C₃‐ und C₄‐Synthesebausteinen aus Hydroxycarbonsäuren

Bernhard Seuring, Dieter Seebàch · Helvetica Chimica Acta · 1977 · 123 citations

Natural Sciences, Chemistry, Natural Product Biosynthesis +7

A highly regioselective conversion of epoxides to halohydrins by lithium halides

Joginder S. Bajwa, Robert C. Anderson · Tetrahedron Letters · 1991 · 106 citations

Natural Sciences, Chemical Engineering, Chemistry +7

Chiral synthesis via organoboranes. 6. Hydroboration. 74. Asymmetric hydroboration of representative heterocyclic olefins with diisopinocampheylborane. Synthesis of heterocyclic boronates and heterocyclic alcohols of very high enantiomeric purity

Herbert C. Brown, J. V. N. Vara Prasad · Journal of the American Chemical Society · 1986 · 96 citations

Natural Sciences, Chemistry, Organic Chemistry +8

Microbiological transformations 37. An enantioconvergent synthesis of the β-blocker using a combined chemoenzymatic approach

S. PEDRAGOSA‐MOREAU, Christophe Morisseau, J. Baratti et al. · Tetrahedron · 1997 · 89 citations

Pharmacy, Biochemistry, Medicinal Chemistry +13

Stereoselectivity of a potent calcium antagonist, 1-benzyl-3-pyrrolidinyl methyl 2,6-dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Kazuharu Tamazawa, Hideki Arima, Tadao Kojima et al. · Journal of Medicinal Chemistry · 1986 · 86 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13