Effect of 21-day exposure of phenobarbital, carbamazepine and phenytoin on P-glycoprotein expression and activity in the rat brain

<i>MDR1</i> Gene Expression in Brain of Patients with Medically Intractable Epilepsy

David M. Tishler, Kenneth I. Weinberg, David R. Hinton et al. · Epilepsia · 1995 · 530 citations

Medicine, Neuroscience, Pharmacology +8

Drug resistance in epilepsy: expression of drug resistance proteins in common causes of refractory epilepsy

Sanjay M. Sisodiya, W-R Lin, Brian Harding et al. · Brain · 2002 · 481 citations · Full text

Medicine, Neuroscience, Pharmacology +13

Overexpression of Multiple Drug Resistance Genes in Endothelial Cells from Patients with Refractory Epilepsy

Stephen M. Dombrowski, Shailesh Y. Desai, Matteo Marroni et al. · Epilepsia · 2001 · 428 citations · Full text

Medicine, Neuroscience, Pharmacology +13

Pregnane X Receptor Up-Regulation of P-Glycoprotein Expression and Transport Function at the Blood-Brain Barrier

Björn Bauer, Anika M. S. Hartz, Gert Fricker et al. · Molecular Pharmacology · 2004 · 291 citations

Medicine, Neuroscience, Pharmacology +16

Relative Activation of Human Pregnane X Receptor versus Constitutive Androstane Receptor Defines Distinct Classes of CYP2B6 and CYP3A4 Inducers

Stephanie Faucette, Tong-Cun Zhang, Rick Moore et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 289 citations · Full text

Medicine, Pharmacology, Biochemical Pharmacology +11