Dipeptidyl peptidase 4 (DPP-4) is expressed in mouse and human islets and its activity is decreased in human islets from individuals with type 2 diabetes

Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells

Helga Ellingsgaard, Irina Häuselmann, Beat Schuler et al. · Nature Medicine · 2011 · 918 citations · Full text

Life Sciences, Endocrinology, Physiology +17

Both subcutaneously and intravenously administered glucagon-like peptide I are rapidly degraded from the NH2-terminus in type II diabetic patients and in healthy subjects

Carolyn F. Deacon, Michael A. Nauck, M. Toft-Nielsen et al. · Diabetes · 1995 · 716 citations

Medicine, Endocrinology, Pharmacokinetics +7

Both Subcutaneously and Intravenously Administered Glucagon-Like Peptide I Are Rapidly Degraded From the NH2-Terminus in Type II Diabetic Patients and in Healthy Subjects

Carolyn F. Deacon, Michael A. Nauck, Lone Pridal et al. · Diabetes · 1995 · 656 citations

Medicine, Endocrinology, Pharmacokinetics +7

Lower blood glucose, hyperglucagonemia, and pancreatic α cell hyperplasia in glucagon receptor knockout mice

Richard W. Gelling, Xiaoqing Du, Darwin S. Dichmann et al. · Proceedings of the National Academy of Sciences · 2003 · 561 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Incretin Secretion in Relation to Meal Size and Body Weight in Healthy Subjects and People with Type 1 and Type 2 Diabetes Mellitus

Tina Vilsbøll, Thure Krarup, Jesper Sonne et al. · The Journal of Clinical Endocrinology & Metabolism · 2003 · 523 citations

Life Sciences, Endocrinology, Physiology +17