Cellular pharmacokinetics of carboplatin and cisplatin in relation to their cytotoxic action

Mechanism of cytotoxicity of anticancer platinum drugs: evidence that cis-diamminedichloroplatinum(II) and cis-diammine-(1,1-cyclobutanedicarboxylato)platinum(II) differ only in the kinetics of their interaction with DNA.

Richard J. Knox, Frank Friedlos, David Lydall et al. · PubMed · 1986 · 499 citations

Chemoprevention Strategy, Chemical Biology, Toxicological Mechanism +19

Early clinical studies with cis-diammine-1,1-cyclobutane dicarboxylate platinum II

A. Hilary Calvert, S.J. Harland, David R. Newell et al. · Cancer Chemotherapy and Pharmacology · 1982 · 485 citations

Oncology, Medicine, Clinical Studies +4

Intraperitoneal Cisplatin with Systemic Thiosulfate Protection

Stephen B. Howell · Annals of Internal Medicine · 1982 · 485 citations

Urology, Genitourinary Cancer, Medicine +11

Toxic effects of cis-dichlorodiammineplatinum(II) in man.

Von Hoff, Richard L. Schilsky, Reichert Cm et al. · PubMed · 1980 · 338 citations

Drug Safety, Medicinal Chemistry, Medicine +15

Pharmacokinetics of adriamycin and tissue penetration in murine ovarian cancer.

Robert F. Ozols, Gershon Y. Locker, James H. Doroshow et al. · PubMed · 1979 · 248 citations

Adriamycin-specific Fluorescence, Tissue Penetration, Medicine +14