Identification of host interactions for phenotypic antimalarial hits

Thousands of chemical starting points for antimalarial lead identification

Francisco‐Javier Gamo, Laura M. Sanz, Jaume Vidal et al. · Nature · 2010 · 997 citations

Hit Identification, Medicine, Malaria +8

Chemical genetics of Plasmodium falciparum

W. Armand Guiguemde, Anang A. Shelat, David C. Bouck et al. · Nature · 2010 · 565 citations · Full text

Biology, Biochemical Taxonomy, Genetics +7

<i>In silico</i> activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen

David Plouffe, Achim Brinker, Case W. McNamara et al. · Proceedings of the National Academy of Sciences · 2008 · 448 citations · Full text

The Open Access Malaria Box: A Drug Discovery Catalyst for Neglected Diseases

Thomas Spangenberg, Jeremy N. Burrows, Paul Kowalczyk et al. · PLoS ONE · 2013 · 333 citations · Full text

Selection Methodology, Medicinal Chemistry, Drug Repositioning +15