Neurotoxicity of reactive aldehydes: The concept of “aldehyde load” as demonstrated by neuroprotection with hydroxylamines

4‐Hydroxynonenal‐Derived Advanced Lipid Peroxidation End Products Are Increased in Alzheimer's Disease

Lawrence M. Sayre, Dawn A. Zelasko, Peggy L.R. Harris et al. · Journal of Neurochemistry · 1997 · 1K citations

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Evidence that 4-Hydroxynonenal Mediates Oxidative Stress-Induced Neuronal Apoptosis

Inna I. Kruman, Annadora J. Bruce‐Keller, Dale E. Bredesen et al. · Journal of Neuroscience · 1997 · 727 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Acrolein is increased in Alzheimer’s disease brain and is toxic to primary hippocampal cultures

Mark A. Lovell, Chengsong Xie, William R. Markesbery · Neurobiology of Aging · 2001 · 447 citations

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Protein‐Bound Acrolein

Noel Y. Calingasan, Kôji Uchida, Gary E. Gibson · Journal of Neurochemistry · 1999 · 401 citations

Life Sciences, Neurology, Neuroscience +17

Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease

Taufika Islam Williams, Bert C. Lynn, William R. Markesbery et al. · Neurobiology of Aging · 2005 · 392 citations

Life Sciences, Neurology, Neuroscience +17