Epidemiology · 2005 · 423 citations · 32 references
Age-adjusted mortality is reduced 2% with each increasing year of age at menopause. In particular, ischemic heart disease mortality is 2% lower. Although the risk of death from uterine or ovarian cancer is increased by 5%, the net effect of a later menopause is an increased lifespan.
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Menopause and Risk of Cardiovascular Disease
William B. Kannel · Annals of Internal Medicine · 1976 · 1.4K citations
Hypertension, Initial Framingham Examination, Gynecology +19
Menopause and the Risk of Coronary Heart Disease in Women
Graham A. Colditz, Walter C. Willett, Meir J. Stampfer et al. · New England Journal of Medicine · 1987 · 1.2K citations
Age at menopause as a risk factor for cardiovascular mortality
Yvonne T. van der Schouw, Y. van der Graaf, Ewout W. Steyerberg et al. · The Lancet · 1996 · 606 citations · Full text