Anais Brasileiros de Dermatologia · 2014 · 25 citations · 4 references
MedicineDermatologySurgeryRegenerative MedicineTissue EngineeringWound HealingPlatelet ActivationPlatelet AdhesionPlatelet FunctionPlatelet PhysiologySkin RegenerationSkin Tissue EngineeringAutologous Platelet ConcentratesDensity Gradient FiltrationFibrin Matrix FormationGrowth FactorsGrowth Factors In RepairPlatelet-rich Plasma InjectionProliferative Phase Of HealingTissue Repair Microenvironment
The platelet-rich plasma (PRP) has proved promising regarding its applicability in dermatology, especially in the healing of chronic ulcers. The autologous platelet-rich plasma is obtained by centrifuging the blood, so that the components are separated by density gradient. The final product is a gel rich in growth factors that act in tissue repair by activating fibroblasts and inducing extracellular matrix remodeling.
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Robert E. Marx, Eric R. Carlson, Ralph M. Eichstaedt et al. · Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology · 1998 · 2.6K citations
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Paola Romina Amable, Rosana Bizon Vieira Carias, Marcus Vinicius Telles Teixeira et al. · Stem Cell Research & Therapy · 2013 · 715 citations · Full text
Platelet gel for healing cutaneous chronic wounds
G. Crovetti, Giovanna Martinelli, M Issi et al. · Transfusion and Apheresis Science · 2004 · 435 citations
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The use of autologous platelet gel to treat difficult‐to‐heal wounds: a pilot study
Laura Mazzucco, D Medici, Massimo Serra et al. · Transfusion · 2004 · 237 citations
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