Journal of Endocrinology · 1963 · 54 citations · 0 references
SpermatogenesisSqualus AcanthiasHigh ConcentrationSummary 11-DeoxycorticosteroneFemale Reproductive FunctionReproductive BiologyReproductive EndocrinologyUnidentified CompoundsMale InfertilityPublic HealthSteroid MetabolismAnimal PhysiologyAndrologyEndocrinologyPharmacologyBiologyPhysiologyMetabolismMedicineEndocrine Research
SUMMARY 11-Deoxycorticosterone has been found in surprisingly high concentration ( ca . 500 μg./100 g.) in the semen of Squalus acanthias . Accompanying steroids are progesterone (8 μg./100 g.), androstenedione (2 μg./100 g.), dehydro epi androsterone (2 μg./100 g.), pregnenolone (14 μg./100 g.), androsterone (< 5 μg./100 g.) and possibly aldosterone (< 1 μg./100 g.); three unidentified compounds were also detected. Only a small proportion ( ca . 5%) of the 11-deoxycorticosterone is present in that portion of the semen which passes an ultrafilter. The remainder is either present as a sperm cell constituent or is bound to extracellular mucoids or proteins.