Salivary neoplasms: Overview of a 35‐year experience with 2,807 patients

TLDR

The authors retrospectively reviewed 35 years of data on 2,807 salivary gland tumor patients, primarily treated surgically with conservative resections when feasible, and documented the distribution of tumors across parotid, submandibular, and upper aerodigestive tract glands. Pleomorphic adenomas accounted for 45 % of cases, predominantly arising in the parotid gland, and the study demonstrated how tumor site, histology, grade, and stage influenced clinical outcomes.

Abstract

We have reviewed a 35-year experience with 2,807 patients treated for salivary tumors which arose in the parotid gland (1,695 patients; 70%), submandibular gland (235 patients; 8%), and seromucinous glands of the upper aerodigestive tract (607 patients; 22%). Pleomorphic adenomas comprised 45% of the total, most of which occurred in the parotid gland. The clinical findings and the distribution of patients according to the histology and the site of origin are summarized. Treatment was surgical and the resection was conservative when possible, depending upon the extent of the tumor. The impact of site, histology, grade, and tumor stage on the results is shown.