Sphingosine 1-phosphate induced anti-atherogenic and atheroprotective M2 macrophage polarization through IL-4

Macrophages Sequentially Change Their Functional Phenotype in Response to Changes in Microenvironmental Influences

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IFN-gamma potentiates atherosclerosis in ApoE knock-out mice.

S Gupta, Ana María Rocandio Pablo, Xinfeng Jiang et al. · Journal of Clinical Investigation · 1997 · 865 citations · Full text

Inflammation, Cytokine, Vascular Disease +15

Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways

Harry Björkbacka, Vidya Kunjathoor, Kathryn J. Moore et al. · Nature Medicine · 2004 · 633 citations

Inflammation, Serum Cholesterol Levels, Immunology +11

Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M

Christina Christoffersen, Hideru Obinata, Sunil B. Kumaraswamy et al. · Proceedings of the National Academy of Sciences · 2011 · 589 citations · Full text

Inflammation, Molecular Physiology, Signal Transduction +14

Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions

Naoya Murata, Kōichi Sato, Junko Kon et al. · Biochemical Journal · 2000 · 399 citations · Full text