Prevalence and Associations of <i>tcpC</i> , a Gene Encoding a Toll/Interleukin-1 Receptor Domain-Containing Protein, among <i>Escherichia coli</i> Urinary Tract Infection, Skin and Soft Tissue Infection, and Commensal Isolates

Abstract

TcpC, a new Toll/interleukin-1 receptor domain-containing protein of uropathogenic Escherichia coli involved in the suppression of innate immunity, was found in 2008. The aim of the present study was to determine the prevalence of tcpC and its association with virulence factors and phylogenetic groups among strains from a collection of 212 E. coli isolates from urinary tract and skin and soft tissue infections and 90 commensal E. coli strains.