Characterization and modulation of sex steroid metabolizing activity in normal human keratinocytes in primary culture and HaCaT cells

Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line.

Petra Boukamp, R T Petrussevska, Dirk Breitkreutz et al. · The Journal of Cell Biology · 1988 · 4.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

Tissue distribution and ontogeny of steroid 5 alpha-reductase isozyme expression.

Anice E. Thigpen, Richard I. Silver, Joseph M. Guileyardo et al. · Journal of Clinical Investigation · 1993 · 728 citations · Full text

Life Sciences, Endocrinology, Genetics +17

Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis

Scott Gottlieb, Patricia Gilleaudeau, Ray A. Johnson et al. · Nature Medicine · 1995 · 614 citations

Medicine, Dermatology, Immunology +16

CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris

Judith R. Abrams, Mark Lebwohl, Cynthia Guzzo et al. · Journal of Clinical Investigation · 1999 · 598 citations · Full text

Life Sciences, Dermatology, Immunology +17

The Involvement of Human Placental Microsomal Cytochrome P-450 in Aromatization

E. Aubrey Thompson, Pentti K. Siiteri · Journal of Biological Chemistry · 1974 · 588 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16