Concepedia

Total Synthesis of the<i>Galbulimima</i>Alkaloid (−)‐GB17

Reed T. Larson, Michael D. Clift, Regan J. Thomson

Angewandte Chemie International Edition · 2012 · 29 citations · 45 references

DOIFull text

Open access

Abstract

A tale of two Michaels: The first enantioselective total synthesis of (−)-GB17 is reported. Construction of this unique naphthoquinolizinone skeleton was achieved by two stereoselective intramolecular Michael additions, one under catalyst control and the other under substrate control.

References

45

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Yujiro Hayashi, Hiroaki Gotoh, Takaaki Hayashi et al. · Angewandte Chemie International Edition · 2005 · 1.2K citations

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Mauro Marigo, Tobias C. Wabnitz, Doris Fielenbach et al. · Angewandte Chemie International Edition · 2005 · 947 citations · Full text

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, , +5

Diphenylprolinol Silyl Ethers as Efficient Organocatalysts for the Asymmetric Michael Reaction of Aldehydes and Nitroalkenes

Yujiro Hayashi, Hiroaki Gotoh, Takaaki Hayashi et al. · Angewandte Chemie · 2005 · 459 citations