Journal of Biomedical Optics · 2008 · 38 citations · 43 references
Natural SciencesBiomedical EngineeringMaterials ScienceAcousticsOptical MaterialsUltrasoundAcoustic ImagingOptical PolymersPhotoacoustic ImagingUltrasonicsUltrasound ImagingUltrasound InstrumentationAcoustic WavesDetectorsFabry-perot ResonatorsPhotoacoustic Imaging InstrumentationSpatial Resolution In Photoacoustic ImagingThermoelastic BehaviorThermoelastic ResponseThree-dimensional Photoacoustic Imaging
Thin polymer etalons are demonstrated as high-frequency ultrasound sensors for three-dimensional (3-D) high-resolution photoacoustic imaging. The etalon, a Fabry-Perot optical resonator, consists of a thin polymer slab sandwiched between two gold layers. It is probed with a scanning continuous-wave (CW) laser for ultrasound array detection. Detection bandwidth of a 20-microm-diam array element exceeds 50 MHz, and the ultrasound sensitivity is comparable to polyvinylidene fluoride (PVDF) equivalents of similar size. In a typical photoacoustic imaging setup, a pulsed laser beam illuminates the imaging target, where optical energy is absorbed and acoustic waves are generated through the thermoelastic effect. An ultrasound detection array is formed by scanning the probing laser beam on the etalon surface in either a 1-D or a 2-D configuration, which produces 2-D or 3-D images, respectively. Axial and lateral resolutions have been demonstrated to be better than 20 microm. Detailed characterizations of the optical and acoustical properties of the etalon, as well as photoacoustic imaging results, suggest that thin polymer etalon arrays can be used as ultrasound detectors for 3-D high-resolution photoacoustic imaging applications.
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Photoacoustic imaging in biomedicine
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