Samarium(III)−Propylenediaminetetraacetate Complex:  A Water-Soluble Chiral Shift Reagent for Use in High-Field NMR

Abstract

Samarium(III)-(R)- or (S)-propylenediaminetetraacetate complex resolved the enantiomer signals of alpha-amino acids on high-field (1)H and (13)C NMR with remarkably less line broadening than was previously reported for the Eu(III) complex of the same ligand. A widely observed regularity between the absolute configuration of enantiomers and the relative shift of their NMR signals is useful for the assignment of absolute configuration.