A facile nmr method for assigning absolute configuration of underivatized α-methyl-α-amino acids using a chiral lanthanoid shift reagent for aqueous solution

Alkylation of amino acids without loss of the optical activity: preparation of .alpha.-substituted proline derivatives. A case of self-reproduction of chirality

Dieter Seebàch, M. BOES, Reto Naef et al. · Journal of the American Chemical Society · 1983 · 390 citations

Natural Sciences, Biochemistry, Chemistry +15

N,O‐Acetals from Pivalaldehyde and Amino Acids for the α‐Alkylation with Self‐Reproduction of the Center of Chirality. Enolates of 3‐Benzoyl‐2‐(<i>tert</i>‐butyl)‐1,3‐oxazolidin‐5‐ones

Dieter Seebàch, Antoine Fadel · Helvetica Chimica Acta · 1985 · 157 citations

Natural Sciences, Chemistry, Medicinal Chemistry +10

Synthesis of optically pure .alpha.-alkylated .alpha.-amino acids and a single-step method for enantiomeric excess determination

W. Kruizinga, John Bolster, Richard M. Kellogg et al. · The Journal of Organic Chemistry · 1988 · 148 citations

Natural Sciences, Biochemistry, Chemistry +11

Enzyme catalysed hydrolysis of dialkylated propanedioic acid diesters synthesis of optically pure ()-α-methylphenylalanine, ()-α-methyl-tyrosine and ()-α-methyl-3,4-dihydroxyphenylalanine

Fredrik Björkling, John Boutelie, Sten Gatenbeck et al. · Tetrahedron Letters · 1985 · 69 citations

Natural Sciences, Biochemistry, Chemistry +9

Enantiomeric resolution of N-methyl-α-amino acids and α-alkyl-α-amino acids by ligand-exchange chromatography

Hans Brückner · Chromatographia · 1987 · 50 citations

Pharmacy, Biochemistry, Chromatographic Analysis +11