Chemoresistance to 5-fluorouracil induces epithelial–mesenchymal transition via up-regulation of Snail in MCF7 human breast cancer cells

The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression

Amparo Cano, Mirna Pérez‐Moreno, Isabel Rodrigo et al. · Nature Cell Biology · 2000 · 3.6K citations

Transcriptional Regulation, Developmental Biology, Signaling Pathway +11

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

Chad J. Creighton, Xiaoxian Li, Melissa D. Landis et al. · Proceedings of the National Academy of Sciences · 2009 · 1.4K citations · Full text

Breast Oncology, Immunology, Immunoediting +16

Snail blocks the cell cycle and confers resistance to cell death

Sonia Vega, Aixa V. Morales, Oscar H. Ocaña et al. · Genes & Development · 2004 · 860 citations · Full text

Cell Death, Snail Favors Changes, Cell Proliferation +17

Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer

Thiruvengadam Arumugam, Vijaya Ramachandran, Keith F. Fournier et al. · Cancer Research · 2009 · 856 citations · Full text

Pancreatic Cancer, Health Sciences, Medicine +15

Snail and Slug Mediate Radioresistance and Chemoresistance by Antagonizing p53-Mediated Apoptosis and Acquiring a Stem-Like Phenotype in Ovarian Cancer Cells

Nawneet K. Kurrey, Swati Jalgaonkar, Alok V. Joglekar et al. · Stem Cells · 2009 · 646 citations · Full text