Cisplatin induces apoptosis through the ERK–p66shc pathway in renal proximal tubule cells

Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis

Marco Giorgio, Enrica Migliaccio, Francesca Orsini et al. · Cell · 2005 · 1.2K citations · Full text

Mitochondrial Function, Biochemistry, Natural Sciences +11

Requirement for ERK Activation in Cisplatin-induced Apoptosis

Xiantao Wang, Jennifer L. Martindale, Nikki J. Holbrook · Journal of Biological Chemistry · 2000 · 673 citations · Full text

Cisplatin nephrotoxicity: molecular mechanisms.

Marie H. Hanigan, Prasad Devarajan · PubMed · 2003 · 389 citations · Full text

Urology, Renal Function, Cisplatin-induced Nephrotoxicity +14

Reciprocal Role of ERK and Nf-κb Pathways in Survival and Activation of Osteoclasts

Tsuyoshi Miyazaki, Hideki Katagiri, Yumi Kanegae et al. · The Journal of Cell Biology · 2000 · 381 citations · Full text

Role and regulation of activation of caspases in cisplatin-induced injury to renal tubular epithelial cells

Gur P. Kaushal, Varsha Kaushal, Xiaoman Hong et al. · Kidney International · 2001 · 266 citations

Urology, Signal Transduction, Cell Regulation +11