Irreversible inhibitors of GABA transaminase induce antinociceptive effects and potentiate morphine

Opiates and endogenous opioid peptides

John Kelly, Raymond Dingledine · Trends in Biochemical Sciences · 1977 · 1.3K citations

Medicine, Neuroscience, Pharmacology +12

γ‐VINYL GABA (4‐amino‐hex‐5‐enoic acid), A NEW SELECTIVE IRREVERSIBLE INHIBITOR OF GABA‐T: EFFECTS ON BRAIN GABA METABOLISM IN MICE¹

Michael J. Jung, Bruce Lippert, Brian W. Metcalf et al. · Journal of Neurochemistry · 1977 · 479 citations

Life Sciences, Biochemistry, Pharmacology +17

KINETIC PARAMETERS OF NARCOTIC AGONISTS AND ANTAGONISTS, WITH PARTICULAR REFERENCE TO<i>N</i>‐ALLYLNOROXYMORPHONE (NALOXONE)

H. W. Kosterlitz, A Watt · British Journal of Pharmacology and Chemotherapy · 1968 · 391 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

Naloxone as a GABA antagonist: Evidence from iontophoretic, receptor binding and convulsant studies

Raymond Dingledine, Leslie L. Iversen, Ellen Breuker · European Journal of Pharmacology · 1978 · 331 citations

Medicine, Neuroscience, Pharmacology +15

THE EFFECT OF 4‐AMINO HEX‐5‐YNOIC ACID (γ‐ACETYLENIC GABA, γ‐ETHYNYL GABA) A CATALYTIC INHIBITOR OF GABA TRANSAMINASE, ON BRAIN GABA METABOLISM <i>IN VIVO</i>

Michael J. Jung, Bruce Lippert, Brian W. Metcalf et al. · Journal of Neurochemistry · 1977 · 217 citations

Life Sciences, Biochemistry, Pharmacology +17