Cytogenetics and Cell Genetics · 2008 · 108 citations · 0 references
Life SciencesGeneticsMolecular GeneticsCytogeneticsHuman GeneticsMedical GeneticsChromosome MappingGene MappingGenetic MappingMolecular CytogeneticsStructural Chromosome AbnormalitiesDna In Situ HybridizationGene Dosage ControlQuantitative In Situ Hybridization
The human antithrombin III (ATIII) structural gene was mapped by in situ hybridization and quantitative analysis of ATIII gene dosage in DNA isolated from carriers of chromosome 1 deletions. These studies indicate that the ATIII structural gene maps to human chromosome q23-q25 and so is likely identical to AT3.