Assignment of the human antithrombin III structural gene to chromosome 1q23–25

S.C. Bock, John F. Harris, I. Balazs, J.M. Trent

Cytogenetics and Cell Genetics · 2008 · 108 citations · 0 references

Concepts

Abstract

The human antithrombin III (ATIII) structural gene was mapped by in situ hybridization and quantitative analysis of ATIII gene dosage in DNA isolated from carriers of chromosome 1 deletions. These studies indicate that the ATIII structural gene maps to human chromosome q23-q25 and so is likely identical to AT3.