Concepedia

Gene Dosage Control

Gene Dosage Control is a molecular engineering strategy that regulates the copy number of a target gene within a host organism to modulate the level of recombinant protein expression.

947

Publications

65.7K

Citations

4.9K

Authors

1.3K

Institutions

Publications per year

2017–2026

134

Parents

Publications

947

Analysis of gene control signals by DNA fusion and cloning in Escherichia coli

M J Casadaban, Stanley N. Cohen · Journal of Molecular Biology · 1980 · 2.5K citations

, , +16

Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals

Seiko Ishida, Jaekwon Lee, Dennis J. Thiele et al. · Proceedings of the National Academy of Sciences · 2002 · 915 citations · Full text

, , +13

Maternal Control of Embryogenesis by <i>MEDEA</i> , a <i>Polycomb</i> Group Gene in <i>Arabidopsis</i>

Ueli Grossniklaus, Jean‐Philippe Vielle‐Calzada, Marilu A. Hoeppner et al. · Science · 1998 · 858 citations

, , +17

The role of gene dosage and genetic transpositions in carcinogenesis

George Klein · Nature · 1981 · 668 citations

, , +14

Hearts From Rodents Exposed to Intermittent Hypoxia or Erythropoietin Are Protected Against Ischemia-Reperfusion Injury

Zheqing Cai, Dominador J. Manalo, E. René Rodríguez et al. · Circulation · 2003 · 550 citations · Full text

, , +16

1–5 of 947

Authors

4.9K

  1. JR
    James R. Lupski

    Baylor College of Medicine, United States

    8 publications · 690 citations

    8

    h-index

  2. YG
    Yoram Groner

    Weizmann Institute of Science, Israel

    6 publications · 297 citations

    6

    h-index

  3. YH
    Yann Hérault

    Centre National de la Recherche Scientifique, France

    6 publications · 226 citations

    6

    h-index

  4. JC
    John C. Lucchesi

    University of North Carolina at Chapel Hill, United States

    6 publications · 803 citations

    6

    h-index

  5. JA
    James A. Birchler

    University of Missouri, United States

    6 publications · 624 citations

    6

    h-index

1–5 of 4.9K

Institutions

1.3K

  1. Centre National de la Recherche Scientifique

    Paris, France

    30 h-index

    126 publications

    11.6K citations

  2. Inserm

    Paris, France

    21 h-index

    85 publications

    5.1K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    21 h-index

    59 publications

    7.9K citations

  4. Harvard University

    Cambridge, United States

    18 h-index

    45 publications

    3.5K citations

  5. National Institutes of Health

    Bethesda, United States

    17 h-index

    79 publications

    6K citations

  6. Baylor College of Medicine

    Houston, United States

    16 h-index

    80 publications

    7.3K citations

  7. University of California, San Francisco

    San Francisco, United States

    15 h-index

    63 publications

    9K citations

  8. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    14 h-index

    40 publications

    1.9K citations

1–8 of 1.3K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 44 publications · 5K citations

    36

    h-index

  2. Journal of Bacteriology

    JB · 50 publications · 2.5K citations

    28

    h-index

  3. Genetics

    44 publications · 2.4K citations

    26

    h-index

  4. PubMed

    Repository · 34 publications · 1.7K citations

    21

    h-index

  5. Journal of Biological Chemistry

    JBC · 20 publications · 1.6K citations

    19

    h-index

1–5