Anesthesiology · 1978 · 202 citations · 0 references
MedicineNeurosciencePharmacologyClinical NeuroscienceNeuropharmacologyNeurophysiologyAcute Ischemic StrokeCerebrovascular DiseaseHypoxic-ischemic EncephalopathyNeuroprotectionNeuroprotective PharmacologyStrokeCerebral Hypoxic-ischemic InjuryCerebral InjuryCerebral Ischemia PharmacotherapyNeural IschemiaRodent Cerebral IschemiaStroke Neuroprotection
The authors studied the effect of thiopental in ameliorating permanent brain damage in monkeys after 16 min of global ischemia of the brain produced by a high-pressure neck tourniquet and systemic arterial hypotension. Intensive care and life support, including monitoring of physiologic variables, w