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Thiopental Amelioration of Brain Damage after Global Ischemia in Monkeys
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1978
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Cerebrovascular DiseaseBrain CirculationSocial SciencesCerebral Vascular RegulationStrokeIntracranial PressurePermanent Brain DamageBrain InjuryNeurologyIschemic SyndromeHigh-pressure Neck TourniquetNeuropharmacologyNeuroprotectionCerebral Blood FlowReperfusion InjuryPharmacologyGlobal IschemiaNeurophysiologyNeuroanatomyNeuroscienceMedicineAnesthesiology
The authors studied the effect of thiopental in ameliorating permanent brain damage in monkeys after 16 min of global ischemia of the brain produced by a high-pressure neck tourniquet and systemic arterial hypotension. Intensive care and life support, including monitoring of physiologic variables, w