Gö6976 inhibits LPS-induced microglial TNFα release by suppressing p38 MAP kinase activation

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

Tetsu Akiyama, Junko Ishida, Shizue Nakagawa et al. · Journal of Biological Chemistry · 1987 · 3.7K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways

Hidenori Ichijo, Eisuke Nishida, Kenji Irie et al. · Science · 1997 · 2.3K citations

Life Sciences, Cell Biology, Molecular Biology +16

Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976

Georg Martiny‐Baron, Marcelo G. Kazanietz, Harald Mischak et al. · Journal of Biological Chemistry · 1993 · 1.6K citations · Full text

Medicine, Molecular Biology, Pharmacology +12

Immortalization of murine microglial cells by a v-raf / v-myc carrying retrovirus

Elisabetta Blasi, R. Barluzzi, V. Bocchini et al. · Journal of Neuroimmunology · 1990 · 1.1K citations · Full text

Life Sciences, Cell Biology, Immunology +8

Extracellular Signal-Regulated Kinase and p38 Subgroups of Mitogen-Activated Protein Kinases Regulate Inducible Nitric Oxide Synthase and Tumor Necrosis Factor-α Gene Expression in Endotoxin-Stimulated Primary Glial Cultures

Narayan R. Bhat, Peisheng Zhang, John C. Lee et al. · Journal of Neuroscience · 1998 · 715 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17