Liposomal thymoquinone effectively combats fluconazole-resistant Candida albicans in a murine model

Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling

Nahed El‐Najjar, Manal Chatila, Hiba Moukadem et al. · APOPTOSIS · 2009 · 279 citations

Inflammation, Reductive Stress, Signal Transduction +14

Oral and intraperitoneal LD50 of thymoquinone, an active principle of Nigella sativa, in mice and rats.

Amein K. Al‐Ali, A. Aziz. M. Alkhawajah, Mohammad Akram Randhawa et al. · PubMed · 2009 · 267 citations

<i>Candida albicans</i> cell surface superoxide dismutases degrade host‐derived reactive oxygen species to escape innate immune surveillance

Ingrid E. Frohner, Christelle Bourgeois, Kristina Yatsyk et al. · Molecular Microbiology · 2008 · 259 citations · Full text

Microbial Pathogens, Fungal Cell Biology, Innate Immune System +18

Anti-inflammatory effect of thymoquinone in a mouse model of allergic lung inflammation

Mohamed El Gazzar, Rabab El Mezayen, John C. Marecki et al. · International Immunopharmacology · 2006 · 226 citations

Asthma, Inflammation, Anti-inflammatory +15

Thymoquinone in liposomes: a study of loading efficiency and biological activity towards breast cancer

Fadwa Odeh, Said I. Ismail, Rana Abu‐Dahab et al. · Drug Delivery · 2012 · 192 citations · Full text

Pharmaceutical Science, Drug Solubility, Tumor Biology +17