Concepedia

Disorder and residual helicity alter p53-Mdm2 binding affinity and signaling in cells

Wade M. Borcherds, François‐Xavier Theillet, Andrea Katzer, Ana Finzel, Katie M. Mishall, Anne Terese Powell, Hongwei Wu, Wanda Manieri, Christoph Dieterich, Philipp Selenko,

Nature Chemical Biology · 2014 · 192 citations · 31 references

DOI

Concepts

References

31

WAF1, a potential mediator of p53 tumor suppression

Wafik S. El‐Deiry, Takashi Tokino, Victor E. Velculescu et al. · Cell · 1993 · 8.4K citations

, , +13

In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2

Lyubomir T. Vassilev, Binh Thanh Vu, Bradford Graves et al. · Science · 2004 · 4.7K citations

, , +15

A System for Stable Expression of Short Interfering RNAs in Mammalian Cells

Thijn R. Brummelkamp, René Bernards, Reuven Agami · Science · 2002 · 4.3K citations · Full text

, , +16

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

Toshiyuki Miyashita, John C. Reed · Cell · 1995 · 4.1K citations · Full text

, , +12

A Third-Generation Lentivirus Vector with a Conditional Packaging System

Tom Dull, Romain Zufferey, Michael T. Kelly et al. · Journal of Virology · 1998 · 3.4K citations · Full text

, , +17