A rapid, sensitive and specific radioimmunoassay for methotrexate

Temporary Remissions in Acute Leukemia in Children Produced by Folic Acid Antagonist, 4-Aminopteroyl-Glutamic Acid (Aminopterin)

Sidney Farber, Louis K. Diamond, Robert D. Mercer et al. · New England Journal of Medicine · 1948 · 1.8K citations

Pharmacy, Pharmacology, Pharmacotherapy +11

Adjuvant Methotrexate and Citrovorum-Factor Treatment of Osteogenic Sarcoma

Norman Jaffe, E Frei, Demetrius Traggis et al. · New England Journal of Medicine · 1974 · 497 citations

Medicine, Oncology, Pharmacology +11

New Approaches to Cancer Chemotherapy with Methotrexate

Howard L. Bleich, Emily S. Boro, E Frei et al. · New England Journal of Medicine · 1975 · 232 citations

Medicine, Oncology, Pharmacology +16

THE BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ACTION AND EFFECTS OF THE FOLIC ACID ANTAGONISTS.

William C. Werkheiser · PubMed · 1963 · 154 citations

Medicine, Biochemistry, Pharmacology +14

Improved therapeutic index of methotrexate with "leucovorin rescue".

Martin Levitt, Mosher Mb, DeConti Rc et al. · PubMed · 1973 · 151 citations

Medicine, Oncology, Pharmacology +9