A specific β3-adrenoceptor agonist induces increased pancreatic islet blood flow and insulin secretion in rats

Tissue distribution of beta 3-adrenergic receptor mRNA in man.

Stéphane Krief, Fredrik Lönnqvist, S. Raimbault et al. · Journal of Clinical Investigation · 1993 · 531 citations · Full text

Life Sciences, Molecular Biology, Physiology +7

Effect of CL-316,243, a thermogenic beta 3-agonist, on energy balance and brown and white adipose tissues in rats

Jean Himms‐Hagen, Jing Cui, E. Danforth et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 1994 · 379 citations

Life Sciences, Pharmacology, Physiology +15

Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent .beta.-adrenergic agonist virtually specific for .beta.3 receptors. A promising antidiabetic and antiobesity agent

Jonathan D. Bloom, Minu Dutia, Bernard D. Johnson et al. · Journal of Medicinal Chemistry · 1992 · 297 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

Molecular cloning and expression of the rat beta 3-adrenergic receptor.

James G. Granneman, Kristine N. Lahners · PubMed · 1991 · 287 citations

Medicine, Biochemistry, Pharmacology +12

Stimulation by glucose of the blood flow to the pancreatic islets of the rat

Leif Jansson, C. Hellerstr�m · Diabetologia · 1983 · 245 citations · Full text

Life Sciences, Endocrinology, Physiology +13