Peptide Nucleic Acid Clamping Versus Direct Sequencing for the Detection of <i>EGFR</i> Gene Mutation in Patients with Non-small Cell Lung Cancer

Abstract

PNA clamping showed a significantly higher detection rate of EGFR gene mutation compared with DS. Higher sensitivity of PNA clamping was not compromised by the loss of predictive power of response to EGFR-TKI.