Antagonistic Effect of A.C.T.H. and Cortisone on the Anticoagulant Activity of Ethyl Biscoumacetate

Abstract

vaccines seem to be the commonest source of these accidents (Byers and Moll, 1948), but similar sequelae have been recorded after inoculation of diphtheria, typhoid, and other bacterial antigens as after the disease itself, again notably whooping-cough. These cerebral accidents are commonly regarded as allergic or protein-shock phenomena, the pre- dominating changes being vascular thrombosis. The hypoxia accompanying severe paroxysms is regarded as an important factor in the causation of whooping-cough encephalopathy, which tends to leave permanent residua (Levy and Perry, 1948). The frequent occurrence of con- vulsions raises the question of an epileptic diathesis or like predisposition, or a trigger mechanism in cerebration which may be released by fever, from whatever cause.