Concepedia

Microencapsulation of Insulin Microcrystals

Sung Hee Choi, Jai-Hyun Kwon, Chan‐Wha Kim

Bioscience Biotechnology and Biochemistry · 2004 · 19 citations · 12 references

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Concepts

Abstract

Insulin microcrystals were encapsulated (microcrystal/PLGA) within poly(lactide-co-glycolide) (PLGA 50:50) by the multiple emulsification solvent evaporation technique and compared with insulin solution microspheres (solution/PLGA) in terms of their morphology, size distribution, drug content, encapsulation efficiency, and stability of insulin during release.

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