Requirement of Intact Disulfide Bonds in Orexin-A-Induced Stimulation of Gastric Acid Secretion That Is Mediated by OX1 Receptor Activation

The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity

Luı́s de Lecea, Thomas S. Kilduff, Christelle Peyron et al. · Proceedings of the National Academy of Sciences · 1998 · 3.9K citations

Life Sciences, Neurobiology, Neuroscience +15

Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems

Christelle Peyron, Devin K. Tighe, Anthony N. van den Pol et al. · Journal of Neuroscience · 1998 · 3.5K citations · Full text

Medicine, Neurobiology, Neuroscience +14

Narcolepsy in orexin Knockout Mice

Richard M. Chemelli, Jon T. Willie, Christopher M. Sinton et al. · Cell · 1999 · 3.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +12

The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene

Ling Lin, Juliette Faraco, Robin Li et al. · Cell · 1999 · 2.6K citations · Full text

Medicine, Neurology, Neuroscience +13

Distribution of orexin neurons in the adult rat brain

Tadahiro Nambu, Takeshi Sakurai, Katsuyoshi Mizukami et al. · Brain Research · 1999 · 1.1K citations

Life Sciences, Neurobiology, Neuroscience +9