Concepedia

Human Safety and Pharmacokinetics of the CFC Alternative Propellants HFC 134a (1,1,1,2-Tetrafluoroethane) and HFC 227 (1,1,1,2,3,3,3-Heptafluoropropane) Following Whole-Body Exposure

Harry Emmen, E.M.G. Hoogendijk, W.A.A. Klöpping-Ketelaars, Hans Muijser, Evert Duistermaat, J.C. Ravensberg, D.J. Alexander, Daxa Borkhataria, G Rusch, Bruno Schmit

Regulatory Toxicology and Pharmacology · 2000 · 63 citations · 9 references

DOI

Concepts

References

9

Stratospheric sink for chlorofluoromethanes: chlorine atom-catalysed destruction of ozone

Mario J. Molina, F. S. Rowland · Nature · 1974 · 4.4K citations · Full text

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Twenty-eight-day Double-blind Safety Study of an HFA-134a Inhalation Aerosol System in Healthy Subjects

Lester I. Harrison, David Donnell, Jean L Simmons et al. · Journal of Pharmacy and Pharmacology · 1996 · 45 citations · Full text

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Safety of Propellants

D.J. Alexander · Journal of Aerosol Medicine · 1995 · 43 citations

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1,1,1,2-Tetrafluoroethane: Repeat Exposure Inhalation Toxicity in the Rat, Developmental Toxicity in the Rabbit, and Genotoxicity in Vitro and in Vivo

Michael D. Collins · Fundamental and Applied Toxicology · 1995 · 32 citations

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Metabolic fate and disposition of 1,1,1,2-tetrafluoroethane (HFC134a) in rat following a single exposure by inhalation

Martin K. Ellis, Lesley A. Gowans, T. Green et al. · Xenobiotica · 1993 · 27 citations

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