Concepedia

Synthesis of a chromogenic proline-containing glycopeptide

Wolfram Steffan, Mike Schutkowski, Gunter Fischer

Chemical Communications · 1996 · 12 citations · 8 references

DOI

Concepts

Abstract

A convenient synthesis of a chromogenic glycopeptide, O-(β-D-glucopyranosyl)-Ser-Pro-4-nitroanilide, involving the direct glycosylation of Fmoc-Ser-OH, coupling of L-proline-4-nitroanilide and sequential deprotection without diketopiperazine formation is reported.

References

8

Synthesis of Glycopeptides, Partial Structures of Biological Recognition Components [New Synthetic Methods (67)]

Horst Kunz · Angewandte Chemie International Edition in English · 1987 · 376 citations

, , +14

Syntheses, Conformations and X‐Ray Structure Analyses of the Saccharide Chains from the Core Regions of Glycoproteins

Hans Paulsen · Angewandte Chemie International Edition in English · 1990 · 244 citations

, , +21

General methods for .alpha.- or .beta.-O-Ser/Thr glycosides and glycopeptides. Solid-phase synthesis of O-glycosyl cyclic enkephalin analogs

Robin Polt, Lajos Szabó, Jennifer Treiberg et al. · Journal of the American Chemical Society · 1992 · 120 citations

, , +13

Building blocks for glycopeptide synthesis: glycosylation of 3-mercaptopropionic acid and Fmoc amino acids with unprotected carboxyl groups

Mikael Elofsson, Björn Walse, Jan Kihlberg · Tetrahedron Letters · 1991 · 91 citations

, , +6

The structure of (xylose)2glucose-O-serine 53 found in the first epidermal growth factor-like domain of bovine blood clotting factor IX.

Sumihiro Hase, Hitoshi Nishimura, Shun‐ichiro Kawabata et al. · Journal of Biological Chemistry · 1990 · 85 citations · Full text

, , +21