Physical Review Letters · 2007 · 184 citations · 28 references
Biophysical ModelingEngineeringDominating Length ScaleCytoskeletonCellular PhysiologyNonlinear ResponseBiological NetworkRheologyBiophysicsCell DivisionMacromolecular MachineCell BiomechanicsCell BiologyPattern FormationComputational NeuroscienceLinear ResponseCell MotilityCellular StructureSystems BiologyMedicine
Despite their importance for the proper function of living cells, the physical properties of cross-linked actin networks remain poorly understood as the occurrence of heterogeneities hamper a quantitative physical description. The isotropic homogenously cross-linked actin network presented here enables us to quantitatively relate the network response to a single filament model by determining the dominating length scale. The frequency dependence of the linear response and nonuniversal form of the nonlinear response reveal the importance of cross-linker unbinding events.
28
Nonlinear elasticity in biological gels
Cornelis Storm, Jennifer J. Pastore, F. C. MacKintosh et al. · Nature · 2005 · 1.6K citations · Full text
Elastic Behavior of Cross-Linked and Bundled Actin Networks
M. L. Gardel, Jennifer H. Shin, F. C. MacKintosh et al. · Science · 2004 · 1.3K citations
Elasticity of Semiflexible Biopolymer Networks
F. C. MacKintosh, Josef A. Käs, Paul A. Janmey · Physical Review Letters · 1995 · 1.1K citations · Full text