Concepedia

Medicines combinations options and regulatory hurdles

Ole J. Bjerrum, Yvonne Gautam, Esben Jannik Bjerrum, Merete Schmiegelow, Harrie C. M. Boonen

European Journal of Pharmaceutical Sciences · 2013 · 11 citations · 17 references

DOI

Concepts

References

17

Effects of a polypill (Polycap) on risk factors in middle-aged individuals without cardiovascular disease (TIPS): a phase II, double-blind, randomised trial

The Lancet · 2009 · 477 citations

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Impact of Dosage Frequency on Patient Compliance

Arsenio H.P. Paes, Albert Bakker, Carmen J Soe-Agnie · Diabetes Care · 1997 · 408 citations

, , +14

Coamorphous Drug Systems: Enhanced Physical Stability and Dissolution Rate of Indomethacin and Naproxen

Korbinian Löbmann, Riikka Laitinen, Holger Grohganz et al. · Molecular Pharmaceutics · 2011 · 361 citations

, , +17

Development of Novel Combination Therapies

Janet Woodcock, Joseph P. Griffin, Rachel E. Behrman · New England Journal of Medicine · 2011 · 247 citations

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Modelling Response Time Profiles in the Absence of Drug Concentrations: Definition and Performance Evaluation of the K–PD Model

Philippe Jacqmin, Eric Snoeck, E.A. van Schaick et al. · Journal of Pharmacokinetics and Pharmacodynamics · 2006 · 161 citations

, , +16