Concepedia

Predicting the toxic potential of drugs and chemicals in silico: A model for the peroxisome proliferator-activated receptor γ (PPAR γ)

Angelo Vedani, Anne-Vérène Descloux, Morena Spreafico, Beat Ernst

Toxicology Letters · 2007 · 29 citations · 20 references

DOI

Concepts

References

20

A new force field for molecular mechanical simulation of nucleic acids and proteins

Scott J. Weiner, Peter A. Kollman, David A. Case et al. · Journal of the American Chemical Society · 1984 · 4.6K citations

, , +17

Comparative molecular field analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins

Richard D. Cramer, David E. Patterson, Jeffrey D. Bunce · Journal of the American Chemical Society · 1988 · 3.9K citations

, , +14

Macromodel—an integrated software system for modeling organic and bioorganic molecules using molecular mechanics

F. MOHAMADI, Nigel G. J. Richards, Wayne C. Guida et al. · Journal of Computational Chemistry · 1990 · 3.8K citations

, , +13

Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism

Béatrice Desvergne · Endocrine Reviews · 1999 · 1.3K citations

, , +10

Construction of 3D-QSAR Models Using the 4D-QSAR Analysis Formalism

A. J. Hopfinger, Shen Wang, John S. Tokarski et al. · Journal of the American Chemical Society · 1997 · 416 citations

, , +17