Organic Letters · 2012 · 21 citations · 26 references
PharmacyMedicinal ChemistrySynthetic Medicinal ChemistryHeterocycle SynthesisHeterocyclic ChemistryMacrocycle SynthesisRetrosynthetic AnalysisAsymmetric Heterocycle SynthesisEnantioselective SynthesisGlycal ChemistryHeterocycle FunctionalizationOne-pot Heterocycle SynthesisSpirocyclic ScaffoldsSpiroheterocycle SynthesisSuzuki - Miyaura Coupling
Substituted benzoannulated spiroacetals were prepared from (2-haloaryl)alkyl alcohols and dihydropyranyl or dihydrofuranyl pinacol boronates using a Suzuki-Miyaura coupling followed by an acid-catalyzed spirocyclization. Application of the reaction to a glycal boronate provides an approach to annulated spiroacetals in enantiopure form.
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Asymmetric spiroacetalization catalysed by confined Brønsted acids
Ilija Čorić, Benjamin List · Nature · 2012 · 522 citations
Intramolecular Alkyne Hydroalkoxylation and Hydroamination Catalyzed by Iridium Hydrides
Xingwei Li, A. Chianese, Tiffany Vogel et al. · Organic Letters · 2005 · 235 citations