High throughput assay for inhibitors of the epidermal growth factor receptor-associated tyrosine kinase

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

Tetsu Akiyama, Junko Ishida, Shizue Nakagawa et al. · Journal of Biological Chemistry · 1987 · 3.7K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay.

Michael C. Alley, Dominic A. Scudiero, Anne Monks et al. · PubMed · 1988 · 3.1K citations

Medicine, Oncology, Pharmacology +14

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

Julian Downward, Yosef Yarden, E. L. V. Mayes et al. · Nature · 1984 · 2.5K citations · Full text

Medicine, Genetics, Molecular Biology +10

[42] Detection and quantification of phosphotyrosine in proteins

Jonathan A. Cooper, Bartholomew M. Sefton, Tony Hunter · Methods in enzymology on CD-ROM/Methods in enzymology · 1983 · 1.2K citations

Life Sciences, Biochemistry, Molecular Biology +10

Isolation of a calcium-dependent 35-kilodalton substrate for the epidermal growth factor receptor/kinase from A-431 cells.

Roy A. Fava, Stanley Cohen · Journal of Biological Chemistry · 1984 · 366 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17