Concepedia

Inhaled nitric oxide down-regulates intrapulmonary nitric oxide production in lipopolysaccharide-induced acute lung injury

Younsuck Koh, Jihee Lee Kang, Wann Park, In Soon Pack, Hui Su Lee, Mi Jung Kim, Chae‐Man Lim

Critical Care Medicine · 2001 · 19 citations · 34 references

DOI

Abstract

Inhaled NO attenuates LPS-induced acute lung injury, possibly by decreasing NO production in the lungs. The mechanism of reducing NO production resulting from inhaled NO may involve, in part, the activities of reactive oxygen species and/or nuclear factor-kappaB.

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