Novel powder formulations for controlled delivery of poorly soluble anticancer drug: Application and investigation of TPGS and PEG in spray-dried particulate system

What is the True Solubility Advantage for Amorphous Pharmaceuticals?

Bruno C. Hancock, Michael Parks · Pharmaceutical Research · 2000 · 1.3K citations

Pharmacy, Pharmaceutical Analysis, Pharmaceutics +14

Large Porous Particles for Pulmonary Drug Delivery

David A. Edwards, Justin Hanes, Giovanni Caponetti et al. · Science · 1997 · 1.2K citations

Pharmacy, Pharmaceutics, Pharmacology +17

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

Alex Sparreboom, Judith van Asperen, Ulrich Mayer et al. · Proceedings of the National Academy of Sciences · 1997 · 880 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

A novel controlled release formulation for the anticancer drug paclitaxel (Taxol®): PLGA nanoparticles containing vitamin E TPGS

Sheng Feng · Journal of Controlled Release · 2002 · 723 citations

Pharmacy, Pharmaceutics, Pharmacology +17

Immunomicelles: Targeted pharmaceutical carriers for poorly soluble drugs

Vladimir P. Torchilin, Anatoly N. Lukyanov, Zhonggao Gao et al. · Proceedings of the National Academy of Sciences · 2003 · 532 citations

Pharmacy, Oncology, Pharmacology +17